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KMID : 0364820080440020135
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Korean Journal of Microbiology
2008 Volume.44 No. 2 p.135 ~ p.139
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Genetic Distribution of Human Noroviruses Detected from Acute Gastroenteritis Patients in Seoul
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Kim Eun-Jung
Kim Moo-Sang
Cheon Doo-Sung
Song Mi-Ok
Kim Min-Young
Park Sang-Hun
Jeong Hae sook
Kim Chul-Joong
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Abstract
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Fecal specimens from acute gastroenteritis in Seoul from 2004 to 2007 were collected and then tested for the
presence of norovirus by RT-PCR. 258 noroviruses were subjected to be futher characterized to sequencing
analysis. The sequencing analysis showed that thirteen genotypes were detected (GII.1, GII.2, GII.3, GII.4,
GII.5, GII.6, GII.8, GII10, GII.12, GII.13, GII.15, GII.16, GII.17) and predominant genotype was GII.4 (76.7%)
in the cases of norovirus detected sporadic acute gastroenteritis in Seoul. By this molecular investigation, genotypic
distribution associated with norovirus infections will be used for control and prevention of norovirus
related diseases.
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KEYWORD
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genotype, norovirus, RT-PCR, sequencing
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